Intelligent Investment

Philadelphia Market

Global Life Sciences Atlas

April 11, 2025 5 Minute Read

commercial-real-estate-Philadelphia

Overview

  • The Philadelphia life sciences cluster is one of the most significant in the U.S., with a strong longstanding presence of the big pharma industry, and has also emerged recently as a top center for cell and gene therapy innovation.
  • Almost 55,000 work in the Philadelphia’s life sciences industry, with nearly 19,000 in life sciences research and development (R&D) roles.
  • Philadelphia has 11.6 million sq. ft. of life sciences lab/R&D space and 1.4 million sq. ft. under construction.
  • Between 2019-2024, Philadelphia life sciences companies secured more than $6.5 billion in life sciences venture capital funding, the eighth-highest amount in the world.
  • Supporting a dynamic life sciences ecosystem are world-renowned universities (University of Pennsylvania, Drexel University, Temple University, among others), leading healthcare institutions (Jefferson, Penn Medicine, Children’s Hospital of Philadelphia) and prestigious research institutes (Wistar Institute, Coriell Institute, Monell Center).
  • In FY 2024 the National Institutes of Health (NIH) allocated almost $1.3 billion—the seventh-highest amount in the U.S.—to organizations in Philadelphia for healthcare and life sciences initiatives.

Submarkets

Philadelphia-Submarket-Map_

Industry Presence

  • The roughly 55,000 people who work in Philadelphia’s life sciences industry comprise 2.2% of total employment in the Philadelphia region, exceeding the 1.4% average for the U.S.
  • More than 2,500 clinical trials completed in region from 2019-2024.
  • Philadelphia life sciences companies secured more than $688 million of venture capital funding invested last year, the ninth-largest amount in global metros.

Life Sciences Venture Capital Investment Trends

Figure 1: Life Sciences Venture Capital Funding

Source: Pitchbook, CBRE Research, Q1 2025.

Life Sciences Market Stats

Figure 2: Market Overview

Source: Pitchbook, CBRE Research, Q1 2025.

Development Pipeline or Activity

Figure 3: Lab/R&D Space Under Construction

Source: Pitchbook, CBRE Research, Q1 2025.

Featured Projects:

  • Spring House Innovation Park
    • Delivering Q2 2025, 48% preleased to Nucleaus Radiopharmaceuticals
    • Building 14 – 106,000 sq. ft.
    • Beacon Capital

Philadelphia Featured Project

  • Avantor
  • Cencora
  • Century Therapeutics
  • GSK
  • Iovance
  • J&J
  • Merck
  • Pfizer
  • SK Pharmateco
  • Spark Therapeutics
  • West Pharmaceuticals
  • Wuxi
  • Children's Hospital of Philadelphia
  • Drexel University
  • Monell Center
  • Penn Medicine
  • Science Center
  • Temple University
  • Thomas Jefferson University
  • University of Pennsylvania
  • Wistar Institute

Global Life Science Markets

  • Local Response | Intelligent Investment

    New Jersey Market

    April 11, 2025

    commercial-real-estate-New Jersey

    The New Jersey life sciences cluster is one of the nation’s most mature, with deep, historical presence of the pharmaceutical industry. Almost 83,000 people work in the local industry, the fourth-largest workforce in the U.S.

  • Local Response | Intelligent Investment

    New York City Market

    April 11, 2025

    commercial-real-estate-New York City

    The New York City life sciences cluster has demonstrated significant growth and momentum over the last several years. Almost 59,000 people work in the industry in New York City proper and its adjacent counties.

  • Local Response | Intelligent Investment

    Washington, DC-Baltimore Market

    April 11, 2025

    commercial-real-estate-Washington DC

    The life sciences cluster stretching across the Washington, D.C.-Baltimore region is one of the most important in the U.S., bolstered by the presence of federal government agencies and world-renown universities.