Seattle, WA

Seattle’s Newest Life Sciences Building 222 Fifth Tops Out

November 15, 2023

Members of the project’s general contractor, MEP, and supporting builders stand atop 222 Fifth. The Seattle Space Needle is in the background

Media Contact

Casey Davison

Corporate Communications, Midwest

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CBRE today announced that 222 Fifth, a 10-story, 197,919 square foot life sciences facility in South Lake Union has topped out. In a ceremony held on November 9th, building ownership, Lincoln Property Company (LPC) & Intercontinental Real Estate Corporation (“Intercontinental”), were joined by trade unions for the project’s general contractor, MEP, and supporting builders. The Class-A property is on schedule to be completed August 2024.

Located directly adjacent to Seattle Center Space Needle, 222 Fifth will have three floors of brand-new move-in-ready Class A laboratory suites ranging in size from 11,222 – 26,696 square feet. The suites can be combined for a total of 73,663 square feet of contiguous built-out lab space. Each suite’s lab will come equipped with brand new lab benches and shelving, built in case work, and a BSC and fume hood (ready) to allow immediate occupancy for tenants, in addition to directly adjacent office workspace.

“LPC & Intercontinental are excited to be topping out 222 Fifth and offering the Seattle life science community brand new, ready-for-science lab suites. These state-of-the-art research suites represent meaningful savings for growing life science companies in Seattle” said Alex Aigner, Senior Vice President with LPC.

222 Fifth will boast robust lab amenities including a common glass wash and autoclave/air and vacuum system/fume exhaust system/emergency power, lab specialized loading dock with dockmaster for lab deliveries, freight elevator to all floors and lab storage. Additionally, the Building features a 9,000 square foot rooftop deck with views of Lake Union, Elliott Bay, and the Olympics for group meetings, lunches or events. Other amenities include a conference room for large meetings, retail on-site, onsite bike parking with shower facilitates, and 24/7 security.

“We’re thrilled to be bringing a new generation life science facility into the market with premier lab infrastructure and best-in-class amenities” said Nicole Griffin, Director, Asset Management with Intercontinental. “The thoughtful design and operations at 222 Fifth will optimize research for tenants while providing key building amenities to attract and retain top talent.”

CBRE Senior Vice President Paul Carr and Senior Vice President Marcus Yamamoto with CBRE’s Healthcare & Life Sciences Group are managing leasing for the property on behalf of LPC & Intercontinental.

“222 Fifth is a one-of-a-kind LEED Gold project in a premier location with an exceptional branding opportunity. The project connects South Lake Union to the Seattle Center with high quality lab space to accelerate Seattle’s vibrant life science community,” said Paul Carr, Senior Vice President with CBRE’s Healthcare & Life Science Group in Seattle. “In addition to the top-of-market lab specifications, 222 Fifth offers unmatched access to amenities including multiple food options, world-class performing arts, and sporting events located in the adjacent Seattle Center.”

Seattle ranked in the top 10 of CBRE’s latest Life Sciences Talent Report, with the sector growing its workforce by 18% from 2017-2022.

About CBRE Group, Inc.
CBRE Group, Inc. (NYSE:CBRE), a Fortune 500 and S&P 500 company headquartered in Dallas, is the world’s largest commercial real estate services and investment firm (based on 2023 revenue). The company has more than 130,000 employees (including Turner & Townsend employees) serving clients in more than 100 countries. CBRE serves a diverse range of clients with an integrated suite of services, including facilities, transaction and project management; property management; investment management; appraisal and valuation; property leasing; strategic consulting; property sales; mortgage services and development services. Please visit our website at