535 Science Drive
Madison, WI 53711
For Lease
41,000 sqft
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Life Sciences For Lease - Available Immediately
Turn-Key Biomanufacturing Facility
Cleanroom: 5 ISO-7 processing rooms totaling 6,000 SF with airlocks, differential pressure sensors, epoxy finishes, redundant HVAC, and MERV 14 + HEPA
Laboratories: BSL-2 and QC lab in cleanroom boundary with casework, clean air, high power capacity, and nearby EM/specialty labs
Validated Cold Storage: Three mapped 2–8°C cold rooms with redundant systems
Shipping/Receiving: Temperature-controlled dual docks, secure material flow, High bay warehouse (ambient) and 2–8°C
Modern office, conference, reception, and support areas
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Chase Brieman
James West
535 Science Drive is a 41,000-square-foot GMP-compliant biomanufacturing facility offering a turnkey solution for life sciences companies seeking high-performance infrastructure in a strategic location. Designed to meet rigorous regulatory standards, the facility features five ISO-7 cleanrooms totaling 6,000 square feet, equipped with airlocks, differential pressure sensors, epoxy finishes, and advanced HVAC systems with MERV 14 and HEPA filtration delivering 30–40 air changes per hour.
ISO-8 spaces are similarly supported with 20 ACH, ensuring optimal environmental control for sensitive processes. In addition to cleanroom capabilities, the facility includes BSL-2 and QC laboratories within the cleanroom boundary, offering clean air, robust power capacity, and proximity to EM and specialty labs. Office and amenity spaces are modern and thoughtfully designed, including conference rooms, reception areas, and support zones that enhance operational efficiency and employee comfort. Validated cold storage is a standout feature, with three mapped 2–8°C cold rooms supported by redundant systems to ensure product integrity.
The shipping and receiving infrastructure is equally robust, featuring temperature-controlled dual docks, secure material flow pathways, and a high-bay warehouse with both ambient and cold storage capabilities.
ISO-8 spaces are similarly supported with 20 ACH, ensuring optimal environmental control for sensitive processes. In addition to cleanroom capabilities, the facility includes BSL-2 and QC laboratories within the cleanroom boundary, offering clean air, robust power capacity, and proximity to EM and specialty labs. Office and amenity spaces are modern and thoughtfully designed, including conference rooms, reception areas, and support zones that enhance operational efficiency and employee comfort. Validated cold storage is a standout feature, with three mapped 2–8°C cold rooms supported by redundant systems to ensure product integrity.
The shipping and receiving infrastructure is equally robust, featuring temperature-controlled dual docks, secure material flow pathways, and a high-bay warehouse with both ambient and cold storage capabilities.
Madison, WI stands out as a thriving economic and cultural center in the Midwest. Anchored by five key industries—advanced manufacturing, healthcare, agriculture and food production, information technology, and biosciences—the region supports over 500,000 residents and thousands of businesses1. Major employers include Epic Systems, UW Health, American Family Insurance, and the University of Wisconsin–Madison, which alone contributes over $30.8 billion annually to the state economy and supports more than 232,000 jobs 2.
The city boasts a remarkably low unemployment rate of 2.7% as of June 2025 3, and a median household income of $76,983 4, reflecting a stable and prosperous labor market. Madison’s business-friendly climate is further enhanced by ongoing infrastructure investments and a highly educated workforce.
Beyond its economic vitality, Madison offers an exceptional quality of life. The city is renowned for its walkable downtown, vibrant arts scene, and diverse culinary offerings. Cultural landmarks like the Madison Museum of Contemporary Art and Frank Lloyd Wright’s Taliesin enrich the urban experience5. The University of Wisconsin–Madison not only drives innovation but also infuses the city with youthful energy, academic excellence, and global connectivity.
Established in 1984, University Research Park (URP) is a nationally recognized technology and research hub affiliated with UW– Madison. It supports over 9,300 jobs statewide and contributes more than $825 million annually to Wisconsin’s economy4. URP is home to a vibrant ecosystem of startups and established firms in biotechnology, engineering, and computational sciences.
The city boasts a remarkably low unemployment rate of 2.7% as of June 2025 3, and a median household income of $76,983 4, reflecting a stable and prosperous labor market. Madison’s business-friendly climate is further enhanced by ongoing infrastructure investments and a highly educated workforce.
Beyond its economic vitality, Madison offers an exceptional quality of life. The city is renowned for its walkable downtown, vibrant arts scene, and diverse culinary offerings. Cultural landmarks like the Madison Museum of Contemporary Art and Frank Lloyd Wright’s Taliesin enrich the urban experience5. The University of Wisconsin–Madison not only drives innovation but also infuses the city with youthful energy, academic excellence, and global connectivity.
Established in 1984, University Research Park (URP) is a nationally recognized technology and research hub affiliated with UW– Madison. It supports over 9,300 jobs statewide and contributes more than $825 million annually to Wisconsin’s economy4. URP is home to a vibrant ecosystem of startups and established firms in biotechnology, engineering, and computational sciences.
Total Space Available
41,000 sqft
Lease Type
Direct
Lease Rate
Contact Broker For Pricing
Get in touch
Chase Brieman
James West