Chapter 1
Employment
2023 U.S. Life Sciences Outlook
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Life Sciences Employment Reaches Record Levels but Growth Slows
U.S. life sciences employment hit a record 2.1 million jobs at the start of 2023. Although the pace of job growth slowed to 4.1% in January 2023 from 6.3% in January 2022, it was still higher than any annual growth rate before 2019. Should a recession take hold, we expect even slower job growth in 2023.
Life sciences’ share of the total U.S. labor force reached a near-record 1.4% last year. Research & development employment—most notably in the biotechnology sector—grew by 8.7% and led the overall industry’s annual job growth.
Life sciences employment is at a record high, but its growth is slowing. Previous cycles suggest any further slowdown in employment won’t be as severe as that of the broader economy.

Since June 2022, industry employment growth has decelerated due to higher interest rates and a pullback in public and private funding for the industry. The life sciences industry added an average of 11,144 jobs per month between June 2020 and June 2022, up from 6,259 in the comparable two-year period prior to the COVID pandemic (2018-2019). In the past six months ending January 2023, however, the monthly average fell to 3,378.
Figure 1: U.S. Life Sciences Employment Trends
Source: U.S. Bureau of Labor Statistics, CBRE Research, February 2023.
Life sciences companies have announced many more layoffs in the first two months of 2023 than in 2022 (Figure 2). Nevertheless, the unemployment rate for essential scientific occupations in life sciences research & development remain well below the total U.S. unemployment rate (Figure 3), suggesting underlying strength in hiring despite the layoff announcements.
Figure 2: Number of U.S. Life Sciences Companies Announcing Layoffs
Source: CBRE Research, February 2023.
Figure 3: 2022 U.S. Unemployment Rates by Occupation
Source: U.S. Bureau of Labor Statistics, CBRE Research, February 2023.
Despite the possibility of a moderate U.S. recession this year, the life sciences industry has historically been resilient to economic downturns. In each of the past three recessions, job losses in the life sciences industry were much more limited and of a shorter duration than overall U.S. job losses. We expect this same trend if a recession takes hold this year.
Figure 4: Life Sciences Employment Levels in Past Three Recessions
(1.00 = employment level in first month of recession)
Source: U.S. Bureau of Labor Statistics, CBRE Research, February 2023.
Previous life sciences job losses were much more limited and of a shorter duration than overall U.S. job losses.

The latest life sciences local employment data through June 2022 shows which U.S. markets had the most strength and momentum entering a slower growth phase since then. In terms of total number of persons employed in the life sciences industry, the San Francisco Bay Area was the leading metro for life sciences employment, followed by Boston/Cambridge, New Jersey, San Diego, Washington, D.C./Baltimore and New York City.
Figure 5: Top 25 Largest Life Sciences Employment Clusters
Source: U.S. Bureau of Labor Statistics, CBRE Research, February 2023.
The San Francisco Bay Area was the leading metro for life sciences employment.
Life Sciences Employment Growth
Figure 6: Top U.S. Markets for Life Sciences Employment Growth, 2019 to Q2 2022
Source: U.S. Bureau of Labor Statistics, CBRE Research, February 2023.
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Julie Whelan
Senior Vice President, Global Head of Occupier Thought Leadership & Research Consulting
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